The BepiColombo mission cleared a major milestone this week in the final stretch of an eight-year interplanetary voyage to Mercury, the hard-to-reach, scorching hot iron world at the Solar System's innermost frontier.

The robotic science mission, with a price tag of nearly $2 billion, is led by the European Space Agency with contributions from Japan and the United States. Since its launch in 2018, BepiColombo has spiraled closer to the Sun using a combination of plasma propulsion and a series of flybys of Earth, Venus, and Mercury. The maneuvers changed the spacecraft's velocity and steered it toward a final encounter with Mercury later this year.

Next time it reaches Mercury, BepiColombo will be traveling at just the right speed for the planet's gravity to capture the spacecraft into orbit. Scientists working on interplanetary missions are accustomed to long waits for scientific payoffs. It took nearly 10 years for NASA's New Horizons spacecraft to travel from Earth to Pluto. It turns out traveling to fleet-footed Mercury and then entering orbit requires more energy, or delta-v, than sending a probe to fly by Pluto.

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Having more than 150 non-human primates at a research center fall ill with diarrhea in a stomach-churning outbreak that flowed for over two years doesn't sound much like good fortune. But for some scientists, it kind of was, providing a heaping pile of valuable data on how they might finally defeat a foul foe.

In a study published in the latest issue of Science Translational Medicine, scientist sifted through the dump of immunological data from the infections, logging new ways to train immune cells to defeat the bacteria behind the outbreak, a type of Shigella. Researchers were able to pluck out specific bits of the bacteria that the immune system could most effectively attack, linking specific target molecules to specific types of germ-busting immune responses. The researchers even precisely homed in on some of the tiny notches within those craggy target molecules where the most potent antibodies attached.

In all, the study "revealed unexpected features of the anti-Shigella antibody response in naturally infected [non-human primates] and represents a step toward the rational design of Shigella vaccine candidates," the authors write.

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The first Japanese citizen to launch into space, Toyohiro Akiyama was also the first commercially sponsored cosmonaut and the world's first journalist to file reports while on a spaceflight.

Akiyama, 84, died last Wednesday, August 26, of lower gastrointestinal bleeding, news agencies in Japan reported. A funeral was held with his close relatives in attendance.

As a correspondent for the Tokyo Broadcasting System (TBS), Akiyama was chosen out of his 162 fellow employees who applied to fly to space in celebration of the network's 40th anniversary. He trained at the Gagarin Cosmonaut Training Center in Star City, located outside of Moscow, and was assigned to the Soyuz TM-11 crew.

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For the first time in more than 30 years, NASA has no firm plans to send any new landers or rovers to Mars. Instead, the agency's near-term focus at the red planet is on aerial drones, a pioneering mode of exploration that didn't seem realistic until a few years ago.

The first real use of drones for science at Mars will come with the SkyFall mission, a fleet of three helicopters set for launch as soon as late 2028. SkyFall's helicopters will ride to the red planet with NASA's Space Reactor-1 "Freedom" mission, which has the primary objective of demonstrating nuclear electric propulsion in deep space.

The launch schedule is aggressive for SR-1 Freedom and SkyFall, projects that didn't even exist in NASA's portfolio six months ago. NASA's plan for the SR-1 Freedom mission, estimated to cost $2.1 billion, calls for repurposing the core module of the canceled Gateway lunar space station into a testbed for nuclear electric propulsion. SkyFall will build on NASA's success with the Ingenuity helicopter, an experimental vehicle that became the first rotorcraft to fly on another world in 2021.

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