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Risks of Parkinson's Disease May Increase With Prolonged Exposure to Road Traffic Noise

A large Danish study found a modest but consistent association between long-term road traffic noise exposure and higher Parkinson's disease risk, with a 3% increase for every 11.5 dB rise in noise at the most exposed side of a home. The Guardian reports: The researchers modeled noise exposure at the most and least exposed exterior of the residence of each participant and calculated the difference in noise levels. The magnitude of the effect was modest but consistent; at the most exposed facade, for every 11.5dB rise in noise level, the risk of Parkinson's disease rose by 3% over the study period. Having a quiet part of the home may mitigate the association between exposure to road traffic noise and higher risk of Parkinson's disease, according to the findings. The study, published in Jama Neurology, included 3.1 million Danish participants aged 40 and over, and followed them for 18 years. It was established using nationwide health register data, making it the largest study on road traffic noise and Parkinson's disease. Previous research linked the rise in neurological disorders, including Parkinson's disease, with exposure to environmental toxins. Environmental risk factors such as air pollution, microplastics and pesticides have become the main focus of prevention strategies. The study is one of the first to make the link to noise pollution.

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Physicists Create First Room-Temperature Quantum Material

alternative_right shares a report from Phys.org: In a study published in Nature, LSU physicists have developed the first room-temperature quantum material capable of distinguishing and transporting different quantum states of light, overcoming one of the biggest challenges in quantum materials research. Led by Associate Professor of Physics Omar S. Magana-Loaiza, the work establishes a general design principle for engineering an entirely new class of quantum materials, opening new possibilities for quantum computing, secure communications, sensing technologies and advanced energy systems.

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Astronauts Take First X-Rays In Space

Astronauts on SpaceX's Fram2 mission successfully captured diagnostic X-ray images in orbit for the first time. The milestone gives space medicine a second imaging option beyond ultrasound and could help future crews diagnose injuries, inspect equipment, and support longer missions to the moon or beyond. Popular Science reports: Commercial off-the-shelf X-ray machines like the ice cooler-sized MinXray TR90BH now allow users to perform scans on subjects far away from traditional facilities. In 2022, [Mayo Clinic researcher Sheyna Gifford] assisted in preparing a crew to successfully generate digital X-rays while experiencing microgravity during a parabolic flight. Gifford's team then spent years collaborating with SpaceX to plan another feasibility study. This time, they didn't want to operate an X-ray machine aboard an aircraft simulating the conditions in space -- they intended to use the equipment during an orbital mission. The process was detailed in a recently published study in the journal Radiology, and focuses on last year's Fram2 mission. Instead of days of medical training, astronauts spent only four hours learning how to use their portable radiography device. They then took preflight X-rays of a hand, forearm, chest, abdomen, and pelvis ahead of their SpaceX Falcon 9 rocket launch on March 31, 2025. Once in orbit, the team calibrated the system before testing their MinXray on the same body parts as well as a smartwatch. Once the crew returned, a trio of independent radiologists reviewed the orbital X-ray images based on their positioning, spatial and contrast resolutions, and general scan quality. Although positioning scores were slightly decreased for the central body images, every other scan held up to similar examples created on Earth. Meanwhile, the astronauts reported that using the machine was easy despite minimal prior coaching. Looking ahead, researchers hope to conduct further X-ray tests during orbital missions, while continuing to reduce the overall size of equipment.

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Indian Scientists Produce Most Detailed 3D Atlas of the Human Brainstem

Scientists at the Indian Institute of Technology, Madras (IIT-M) have created what they describe as the world's most detailed 3D cellular atlas of the human brainstem, linking whole-brain MRI views to individual neurons across more than 500 tissue sections. The free online atlas, called Anchor, could help researchers better understand diseases such as Alzheimer's, Parkinson's, stroke, and SIDS by showing how healthy and diseased brain tissue differs cell by cell. The BBC reports: Built from high-resolution microscope images rather than costlier molecular techniques, it creates a detailed three-dimensional map of the brainstem, identifying more than 200 clusters of brain cells and nerve pathways. Eight chemical markers help distinguish different cell types, producing one of the clearest pictures yet of this vital, but poorly, understood part of the brain. The brainstem occupies only a sliver of the brain, yet it keeps people alive. It links the brain to the spinal cord and controls breathing, heartbeat, sleep, wakefulness and movement. [...] Users can zoom from the whole brainstem seen on MRI down to individual neurons while maintaining their precise spatial relationships. The researchers have made the atlas freely available online, hoping it becomes a reference tool for neuroscientists, neurologists and neurosurgeons worldwide. Its applications could also extend well beyond anatomy. By comparing healthy brainstem maps with diseased tissue, scientists may better understand disorders ranging from Parkinson's disease and stroke to Alzheimer's disease and sudden infant death syndrome (SIDS). More precise maps could also help neurosurgeons navigate one of the brain's most delicate regions with greater confidence.

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Surprised doctors find 10-inch worm in man's groin during elective surgery

When surgeons dug into a man's groin to repair a painless bulge, they made the unexpected discovery of a living, 10-inch-long (26 cm) worm snug in his abdomen. Adding to the oddity, the man told the surgeons that this had actually happened to him before, according to a case report in the New England Journal of Medicine.

The 71-year-old man had opted to have surgery to repair the bulge, which was an inguinal hernia. These types of protrusions are fairly common, particularly in older men, and occur when a small amount of abdominal contents, such as fat or a bit of intestines, slips through a gap or weak point in the muscles and tissues of the abdominal wall. This bodily leakage creates an external bulge that, in some cases, can be painful and uncomfortable. If the bulge's contents become stuck and pinched off, it can even create a life-threatening situation called a strangulated hernia. But, in other cases, the escaped innards are painless and loose and can be temporarily put back in place by simple, gentle massage.

Most people with inguinal hernias will need surgery at some point to patch up their weak abdominal wall. But, for older men with no pain or discomfort, doctors may suggest watchful waiting, delaying surgery until the need is clear. This was the case for the man. But he elected to repair the inguinal hernia, which was on his right side.

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ยฉ CDC |John H. Cross

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