NASA has selected 12 new investigations to help support human explorers in space. Six will help advance the ability to produce food off-planet, while another six advance the understanding of how unique conditions associated with space exploration can impact the health and physiology of astronauts.  

The six food-focused investigations, supported by the agency’s Space Crops grants, advance NASA’s goal of harnessing the power of plants to enhance quality of life for humans in space, as well as to enable lunar and Mars exploration. Four of the space crops proposals focus on studies of edible plants and how their growth, physiology, and associated microbial communities are affected by environmental conditions in space or on other planetary bodies.

Another proposal involves understanding mechanisms by which certain plant species, called resurrection plants, can withstand extreme, dry conditions. The last space crops proposal builds on previous studies on the International Space Station to uncover functions of algal genes, segments of DNA controlling algae survival, whose expression is modified by spaceflight. Such studies can help scientists integrate biological-based solutions into space life-support systems.

The second set of six proposals fall under the agency’s Biological and Physical Sciences Division’s focus on precision health, which seeks to unravel the mechanisms by which space exploration affects health and well-being. One proposal studies how lunar dust exposure impacts respiratory, immune, and inflammation responses.  A second proposal identifies repurposed drugs that can mitigate the effects space travel has on health and physiology.

Two more of the research proposals look at how radiation combined with other stressors affects age-relevant characteristics seen in various organ and physiological systems. The final two proposals assess molecular and cellular changes induced by stressors in space that can alter gene expression or protein function. The research will identify ways to mitigate health issues and develop early-warning detection systems to notify crew of potential concerns.

The principal investigators who conduct the space biology studies come from 10 institutions across eight states. Nine of the awards are for investigators who are receiving funding from the Space Biology Program for the first time.

Selected Space Crops Investigations

• Jannell Bazurto, University of Minnesota
  Cultivating the Cosmos: Investigating Plant-Microbe Dynamics for Sustainable Space Farming
• Miranda Haus, Michigan State University
  Investigating Legume Crop Rotations and Microbial Interactions in Regolith Simulants
• Andrew Settles, NASA Ames Research Center
  Genetic Mitigation of Spaceflight Stressors on Production of Chlamydomonas
• Christopher Taylor, Ohio State University
  Hydroponic Microbes in a Low Carbon, High-Radiation Environment; Identifying the Genetic Determinants of Water- and Plant-Associated Microbial Survival in Extraterrestrial Environments
• Robert VanBuren, Michigan State University
  Leveraging the Natural Resilience of Resurrection Plants for Space Bioregenerative Systems
• Shuyang Zhen, Texas A&M AgriLife Research
  Environmental Optimization and Cultivar Selection to Enhance Dwarf Tomato Growth and Stress Tolerance for Space Agriculture

Selected Precision Health Investigations

• Archana Dhasarathy, University of North Dakota
  Epigenetic Memory as an Adaptive Mechanism to Microgravity and Radiation Exposure
• Andrij Holian, University of Montana
  Contribution of Aging to Particle-Induced Chronic Inflammation
• Mert Gur, University of Pittsburgh
  Probing Pathogenic Mutations Under Spaceflight-Relevant Stressors Via All-Atom Molecular Dynamics Simulations
• Grace O’Connell, University of California
  Persistent Spine Health Impacts of Microgravity and Radiation Following Recovery
• Satoshi Okawa, University of Pittsburgh
  Investigating Space Flight-Induced Brain-Heart Axis Aging and Identifying Repurposed Drugs to Mitigate Its Effects
• Sanghee Yun, Ph.D., The Children’s Hospital of Philadelphia
  Spaceflight-Relevant Hypercapnia Effects on Space Radiation- and Social Isolation-Induced Biological Aging: A Systems Biology Analysis of Multiple Aging Hallmarks

When fully implemented, more than $7 million in grant money will be awarded throughout fiscal years 2026-2030. These awards were made in response to research proposals submitted to ROSES-2024: Program Element E.9: Space Biology Research Studies (NNH24ZDA001N-SBR).

To learn more about NASA’s biological and physical research in space, visit: https://science.nasa.gov/biological-physical/

NASA is bringing artificial intelligence to the study of the Moon, helping researchers transform how they analyze the Moon’s surface. In an ongoing collaboration with IBM Research and several academic institutions, NASA has launched the NASA-IBM Lunar Foundation Model, among the first open-source AI models built specifically for lunar science. The model, trained primarily on data from NASA’s Lunar Reconnaissance Orbiter (LRO), is hosted publicly on Hugging Face for anyone to use, with the complete codebase available on GitHub for testing and experimentation.

The NASA-IBM Lunar Foundation Model supports the next generation of lunar science by helping researchers quickly analyze vast quantities of data to better understand the Moon’s surface. Using the model as a mapping tool, researchers can rapidly develop actionable strategies for evaluating the Moon’s rugged surface, understanding its geological past, and planning future lunar research.

“NASA has spent decades building an extraordinary scientific record of the Moon, but collecting data is only part of the job,” said Kevin Murphy, chief science data officer and acting chief data and AI officer at NASA Headquarters in Washington. “We also have to make data easier for scientists to explore and use. The NASA-IBM Lunar Foundation Model shows what’s possible when we bring AI to NASA’s petabytes of scientific data. That’s a real opportunity we see with AI: turning large-scale data into new discoveries.”

Unlike traditional models that require building and training specialized algorithms from scratch for specific tasks, foundation models are pre-trained on vast, unlabeled datasets. The broad knowledge they acquire through pre-training allows them to generalize across multiple scientific domains through quick fine-tuning, making foundation models both versatile and efficient in accelerating scientific research.

Data collected by NASA’s LRO over the past 17 years was well-suited for training this foundation model because it covers most of the lunar surface in detail. The data produced from the LRO mission is larger than all other NASA planetary missions combined, capturing an almost seamless, high-resolution mosaic of the entire Moon. The NASA-IBM model was trained on roughly 2 million image tiles from this dataset, comprising more than 1 million high-resolution camera images at 1-meter resolution and nearly 964,000 multispectral images at 100-meter resolution. The model also was trained on high-resolution Moon imagery and terrain data from multiple other missions such as NASA’s GRAIL (Gravity Recovery and Interior Laboratory), NASA’s Lunar Prospector, and JAXA’s (Japan Aerospace Exploration Agency) Selenological and Engineering Explorer.

Because the foundation model is already pre-trained on this dataset, planetary scientists can adapt the model to many different lunar research tasks such as mapping craters, spotting young volcanic features, and estimating where ice may exist near the lunar poles by using only small amounts of labeled data. For researchers who study the Moon’s polar ice, the NASA-IBM model can help them estimate where ice patches are likely to be stable, on and below the surface. Dark areas like the Moon’s permanently shadowed regions remain cold enough to trap and preserve ice for up to billions of years. Studying these areas offers insight into the Moon’s history and presents an opportunity to map potentially usable resources for future space exploration.

While the Moon is thought to no longer be volcanically active, it once experienced dynamic geological processes. For researchers studying lunar volcanism, the NASA-IBM model accelerates the identification of unusual looking volcanic features known as irregular mare patches. Because these structures appear relatively young, they challenge established timelines for lunar cooling, and mapping them could help scientists piece together a more accurate understanding of the Moon’s thermal evolution.

The model also can map surface features, such as craters, more efficiently than manual methods. Every crater is formed by an impact, making crater counts and measurements essential for dating the lunar surface and reconstructing solar system history. The foundation model helps speed up the process of identifying and measuring craters, allowing scientists to focus on interpreting findings and determining their implications for exploration.

Overall, the model matched or exceeded the performance of several other strong baseline models across all evaluated tasks, achieving comparable results on crater mapping and segmentation of irregular mare patches, while demonstrating a clear advantage on estimating polar ice stability.

The NASA-IBM Lunar Foundation Model is part of the agency’s Office of the Chief Science Data Officer’s strategy for AI for science — a larger, ongoing collaboration between NASA and IBM aimed at using advanced AI to explore our planet and solar system. It joins a growing collection of AI models developed through this partnership, including:

• The Prithvi Models: a family of models pre-trained on Earth observation data and designed to support applications such as disaster monitoring, flood mapping, crop yield prediction, and hurricane prediction.
• The Surya Model: a heliophysics model trained on high-resolution solar observation data to predict space weather phenomena such as solar flares which can disrupt power grids and satellite operations.

Within NASA, the Impact AI team at the agency’s Marshall Space Flight Center in Huntsville, Alabama, collaborated with scientists in the agency’s Science Mission Directorate Planetary Science Division, NASA’s Goddard Space Flight Center in Greenbelt, Maryland, and NASA’s Ames Research Center in California’s Silicon Valley, to build the NASA-IBM model. The model is an example of open science in action, uniting experts from NASA, industry, and academia to turn raw data into a resource for lunar discovery. To support the global research community, the team released comprehensive machine learning-ready pre-training datasets and benchmark collections alongside the model, which is integrated into the open-source TerraTorch toolkit. Supported by a companion paper available on Hugging Face, this open release ensures reproducible research and equips scientists worldwide to build, compare, and refine AI models for the future of lunar exploration.

The science team, assembled by NASA Headquarters, included experts from the Universities Space Research Association in Huntsville, Alabama; the SETI Institute in Silicon Valley, California; the University of Maryland, Baltimore County in Catonsville, Maryland; Howard University in Washington, D.C.; NASA’s Science Mission Directorate Planetary Science Division; NASA Ames; and NASA Goddard.

For more information about NASA’s strategy of developing foundation models for science, visit:

https://science.nasa.gov/artificial-intelligence-science

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NASA is seeking proposals to advance the technology and infrastructure needed to explore the Moon and establish a Moon Base in the lunar South Pole region.

Announced on Tuesday, Sept. 8, the solicitation targets capability gaps, including power generation, oxygen extraction, and producing materials on the Moon required for construction and operations. These technologies are essential to making humanity’s next great leap in lunar exploration.

“NASA is accelerating the development of key technologies and closing critical gaps needed for long-term human exploration at the Moon,” said Greg Stover, director of NASA’s Advanced Research and Technology Division. “Partnering with industry will strengthen the U.S. industrial base as we mature the capabilities and infrastructure needed for a sustainable lunar presence.”

The NextSTEP-3 Broad Agency Announcement Appendix A: Lunar Enabling Infrastructure Accelerator solicitation aims to mature and demonstrate capabilities in five areas:

• Vertical solar array technology that can provide consistent power generation, management, distribution, and energy storage.
• In-situ resource utilization oxygen from regolith production to extract usable oxygen molecularly bonded to rock and dust covering the Moon’s surface.
• Radioisotope Stirling generator, a type of nuclear energy technology that uses heat from fissile materials to produce electric power for operating spacecraft systems in the darkest, dustiest, and most remote places.
• In-space advanced manufacturing to reduce reliance on resupply missions from Earth and to optimize mission flexibility and resilience on the Moon.
• Innovative nanomaterials production to advance the commercial availability and quality of nanomaterials that can be used in lunar exploration.

The solicitation intends to cultivate U.S.-led capabilities while maintaining full and open competition among private industry, academic institutions, and not‑for‑profit entities, as well as international partners participating through U.S.-led teams. 

NASA may apply insights gained from the resulting contracts of this solicitation, such as technical data, and demonstration results, to shape future acquisition strategies.  

To learn more about NextSTEP-3, visit:

https://go.nasa.gov/4x20o3t

-end-

Rob Margetta
Headquarters, Washington
202-358-0918
robert.j.margetta@nasa.gov

NASA will provide live coverage of the launch and docking of a Roscosmos cargo spacecraft carrying about three tons of food, fuel, and supplies for the crew aboard the International Space Station.

The unpiloted Progress 96 resupply spacecraft is scheduled to launch at 12:15 p.m. EDT (9:15 p.m. Baikonur time), Wednesday, Sept. 9, on a Soyuz rocket from the Baikonur Cosmodrome in Kazakhstan. NASA’s live launch coverage will begin at 12 p.m.

After a two-day trip to the space station, Progress will dock autonomously to the Poisk module’s space-facing port at 2:37 p.m., Friday, Sept. 11. NASA’s arrival coverage will begin at 1:45 p.m.

NASA will stream these events live through a variety of platforms. Learn where to watch online:

https://www.nasa.gov/live

The spacecraft will remain docked to the orbiting laboratory for about five months before departing to re-enter Earth’s atmosphere, where it will harmlessly burn up over the Pacific Ocean.

Before Progress 96 arrives, the Progress 94 spacecraft will undock from the space station at approximately 11:18 a.m., Monday, Sept. 7, for its departure and planned destructive re-entry. NASA will not stream coverage of Progress 94 undocking.

For more than 25 years, people have lived and worked continuously aboard the International Space Station, advancing scientific knowledge and making research breakthroughs not possible on Earth. The space station helps NASA understand and overcome the challenges of human spaceflight, expand commercial opportunities in low Earth orbit, and build on the foundation for long-duration missions to the Moon, as part of the Artemis program, and to Mars.

Learn more about the International Space Station, its research, and crew, at:

https://www.nasa.gov/station

-end-

Joshua Finch / Jimi Russell
Headquarters, Washington
202-358-1100
joshua.a.finch@nasa.gov / james.j.russell@nasa.gov

Sandra Jones
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov

4 Min Read

Galactic Gems Glisten in New Gallery From NASA’s Chandra

Galaxies are like cosmic gems, each with characteristics including size and shape that make them distinct. A new gallery released today from NASA’s Chandra X-ray Observatory and other telescopes displays a collection of galactic images that showcase this variety.

Astronomers put galaxies into three main categories: spirals like our own Milky Way with arms emanating from their cores, ellipticals that are older and likely the results of mergers, and irregulars that can encompass a wide range of galactic phenomena.

See full gallery

Just as gems reveal the history of Earth through how they were forged over billions of years, these galactic gems are a way to study Earth’s place in our home galaxy of the Milky Way. By looking outward to other galaxies, we learn more about our own – including clues to its past and future.

There are 16 new images in this galactic gallery. Each one contains X-ray data from Chandra that has been collected across Chandra’s decades in space. This high-energy data has been combined with data from telescopes such as NASA’s James Webb and Hubble Space Telescopes, IXPE (Imaging X-ray Polarimetry Explorer), Neil Gehrels Swift Observatory, NuSTAR (Nuclear Spectroscopic Telescope Array), and others both on the ground and in space.

X-rays are critical for the study of galaxies, revealing unique and important information about these cosmic building blocks. For example, Chandra exposes gas that has been superheated to millions of degrees by winds from massive stars, the outflows from supermassive black holes, and the debris from exploded stars. These are key sources of elements in our bodies, in the air we breathe, and the planet we live on. Chandra also sees some of the hottest and most energetic galactic phenomena in the universe, forming a more complete picture of how galaxies live, interact, and evolve when combined with data from other types of light and telescopes.

Spiral and star-forming engines

Face-on spiral galaxies like Messier 33 and NGC 3938 offer unobstructed views of places where energetic pairs of stars and cosmic explosions live along spiral arms. Barred spirals like NGC 1672 and NGC 1385 show how central bar-shaped collections of stars, gas, and dust funnel fuel inward to ignite bursts of star formation. NGC 4725 reveals how star formation can be triggered by a previous collision with another galaxy. Meanwhile, edge-on views of NGC 4631 (the Whale Galaxy) and the starburst Messier 82 (the Cigar Galaxy) showcase giant halos and superwinds of million-degree gas driven thousands of light-years into space by intense explosions of stars, enriching surrounding intergalactic space with vital elements.

Active galactic nuclei, black hole outflows

Powerful, growing black holes in the cores of their host galaxies, known as active galactic nuclei, send energy outward in outbursts and jets that impact entire galaxies. In Centaurus A, Chandra and IXPE data expose a high-energy particle jet blasting tens of thousands of light-years into space from its central engine. In Messier 106, jets from the supermassive black hole heat surrounding gas to create spiral arms that are different from those typically found in spiral galaxies. Meanwhile, the iconic Sombrero Galaxy (Messier 104) highlights a supermassive black hole embedded in a colossal stellar bulge, where Chandra’s X-rays map a diffuse halo of million-degree gas and hot stellar remnants surrounding its sweeping dust lanes.

Collisions, mergers, cosmic disruptions

The gallery also showcases galaxies undergoing extreme gravitational transformations. A direct impact in Arp 143 acts like a cosmic bullseye, creating an expanding ring galaxy and triggering waves of star birth. Violent mergers, such as NGC 3256 and the dust-shrouded starburst II Zw 096, reveal the kind of chaotic galaxy collisions that dominated the early universe and offer a preview of the Milky Way’s distant future merger with nearby galaxy Andromeda. NGC 1569 acts as a local laboratory for studying early universe starbursts, NGC 660 showcases a rare “polar ring” galaxy where a ring of stars orbits over its poles, and Messier 90 shows a spiral galaxy plowing through the Virgo Cluster, having its star-forming gas violently stripped away.

NASA’s Marshall Space Flight Center manages the Chandra program. The Smithsonian Astrophysical Observatory’s Chandra X-ray Center controls science operations from Cambridge, Massachusetts, and flight operations from Burlington, Massachusetts.

Read more from NASA’s Chandra X-ray Observatory

To learn more about Chandra, visit

https://nasa.gov/chandra

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Some of Earth’s microbes likely to hitch a ride to space with human explorers could survive in the shaded nooks and crannies of the Moon’s South Pole region, NASA scientists say. 

Published on Aug. 19, 2026, in Science Advances, these findings highlight a need to better understand microbial persistence in extreme lunar environments. As humans build a permanent presence on the Moon, it may become difficult to distinguish ancient lunar chemistry from contamination delivered by visiting astronauts. The concern extends beyond the Moon and on to Mars, scientists say. 

“Humans are natural explorers, and with them come their voices, their memories … and their microbes,” said Prabal Saxena, a planetary scientist who led the study from NASA’s Goddard Space Flight Center in Greenbelt, Maryland. “For some scientists, myself included, that reality can be unsettling. But it also creates an opportunity to turn an imperfect situation into a useful experiment.”

Bringing microbes along is unavoidable: Humans have, on average, 1 million bacteria living on each patch of skin the size of a pencil eraser, for example. These bacteria vent from spacesuits and habitats. Though the paper’s authors worry about contamination interfering with the search for chemical clues to ancient geology or biology, they also argue that the Moon should be used as a natural lab. In shaded areas around the South Pole, scientists could carefully test the real-life limits of microbial survival in an environment that can’t easily be reproduced on Earth. 

Before any surface science can happen, scientists need a baseline measurement of what contaminants humans bring, the authors say.

“We need to understand what was there before us, because when we go to Mars to search for signs of life beyond our planet, we will want to make sure it’s not stuff we brought,” said Andrew Needham, a NASA Goddard-based paper co-author who is an Artemis contamination‑control scientist for lunar samples.

Even with strict sterilization procedures, some organisms are stubbornly resilient. A good example is Aspergillus niger, which is a fungus that thrives in warm, damp places like household bathrooms and heating, ventilation, and air conditioning systems. Astronauts have sampled it inside the International Space Station, and experiments demonstrate that the fungus can survive outside the station as well. Aspergillus niger was one of five microbes, including bacteria and fungi, selected for this study because of its known toughness in spaceflight environments. 

That microbes survived on the space station’s exterior surprised scientists. These species are typically not considered “extremophiles” that can withstand harsh conditions, such as the vacuum of space, according to Aaron Regberg, a geomicrobiologist at NASA’s Johnson Space Center in Houston.

“I would have expected these microbes to have dried out,” said Regberg, who studies space station bacteria and was a co-author on the paper.

He pointed out that NASA often bakes robotic spacecraft at temperatures above 400 degrees Fahrenheit to reduce the number of living organisms on them. But that’s not possible with astronauts, so contamination concerns take on new meaning in crewed exploration of the Moon’s south polar environment.

A clearer picture of where microbes might survive comes from understanding how sunlight behaves at the poles. Survival in this study means the microbe can stay alive for at least one Earth day, which does not mean that it can grow and reproduce.

Because the Moon has a very small tilt on its axis, the view from its poles is of a Sun that appears to hover just above the horizon, skimming the surface like a flashlight laying on a table. As a result, elevated parts of the surface, including crater ridges, mountains, and even small bumps, block light from reaching low-lying terrain. This produces pockets of shadowed areas that can remain cold and preserve water, as well as shield fragile molecules and possible microorganisms from lethal radiation.

With that scientific context in mind, the team set out to test which Earth microbes could survive extreme polar conditions. They focused on organisms commonly found in spaceflight environments and those common on human skin. Besides Aspergillus niger, these included Bacillus subtilis, Staphylococcus aureus, Deinococcus radiodurans, and several species of Fusarium. Based on an analysis of previous studies, the scientists noted the maximum amount of heat and ultraviolet (UV) radiation each organism can withstand.

Then, the organisms were tested in simulations of three regions near the lunar South Pole — Nobile Rim, Connecting Ridge, and De Gerlache Rim. Those simulations used detailed environmental maps built from elevation and temperature data collected by instruments aboard NASA’s Lunar Reconnaissance Orbiter, combined with models of how radiation strikes the surface.

The models showed maps of “survivable niches” that range in size from a miles-wide crater floor to an astronaut’s boot print. Aspergillus niger, which was most resistant to UV radiation, was able to survive even in areas with some sunlight exposure. UV radiation is so deadly to most microbes that it’s used for sterilization in hospitals. 

“When we think of the Moon, we don’t typically think of biology,” said Heather Graham, a paper co-author at NASA Goddard who helps develop tools and techniques for detecting biology that may look nothing like Earth’s. “But the Moon is a place where a cell can survive, so our first exploration of these sites should pay extra attention to our microbial hitchhikers and work hard to characterize lunar chemistry before our visits change what we will find.”

The authors note that while some microbes can survive in a dormant state in regions around the South Pole, and thereby confuse some future scientific investigations, there is no evidence the Moon has key ingredients to sustain growth and replication. Such ingredients include liquid water, which typically requires an atmosphere and moderate temperatures.  

For more information, visit:

https://science.nasa.gov/astrobiology

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International Observe the Moon Night, Sept. 19, 2026

Each year, observers around the world come together to celebrate Earth’s Moon through direct observations, hands-on activities, lunar-themed music, artwork, readings, and more.

The Moon

From lighting up our skies to preserving evidence of our solar system’s history, Earth’s closest neighbor plays a pivotal role in the study of our planet and beyond.

About the Author

Lonnie Shekhtman

Senior Science Writer

Shekhtman helps communicate NASA planetary science to the world through news and feature stories on NASA.gov, videos for NASA+ and YouTube, and by working with the media. She reports on lunar and Mars science and exploration; NASA’s search for life; missions to Venus, Titan, and Jupiter’s Trojan asteroids; and many other topics related to NASA’s exploration of our solar system and beyond.

The International Space Station has been busy throughout 2026, as it continues to be a bustling workspace for astronauts conducting a variety of scientific experiments that lay the groundwork for missions to the Moon and beyond.

NASA’s Artemis II mission in April was the first crewed flight around the Moon in more than 50 years, marking a major milestone for humanity’s return to the lunar surface. While the mission validated key systems needed for future deep space human exploration, work aboard the International Space Station continues to support those goals. Astronauts on the orbiting laboratory are testing technologies, studying how the human body adapts to long-duration spaceflight, and conducting experiments to help ensure crews can live and work safely in deep space. Research aboard the space station, coupled with Artemis and Moon Base programs, will continue to demonstrate how NASA is preparing for sustained astronaut exploration of the Moon and, eventually, Mars.

Optimizing space technology 

Astronauts aboard the International Space Station demonstrate and optimize innovative technologies to support exploration missions, reduce the technology footprint, and fine-tune systems ahead of travel beyond low Earth orbit.

Exercise equipment is important for long-duration spaceflight. On average, astronauts lose between 1% and 1.5% of their bone density each month while in microgravity, increasing the potential risk for fractures and other bone-related issues. Regular exercise can help counteract these effects and keep astronauts healthy. The European Enhanced Exploration Exercise Device (E4D) is a compact, versatile system now being tested aboard the space station for exploration crews. The system supports a variety of exercises, can simulate different gravity levels and may lead to even more compact exercise technology for exploration crews. 

During deep space missions, astronauts may need medical care but could be too far from Earth to receive a resupply spacecraft with additional equipment. To prepare for that possibility, researchers are testing medical technologies aboard the station. One of these investigations, the Intravenous Fluid Generation – Mini (IVGEN Mini),evaluates producing intravenous (IV) fluids using the station’s potable water supply. Because commercially available IV fluids have a shelf life of only about 16 months, successful demonstrations of this technology could help meet medical needs while reducing launch mass and volume. 

Medical care is one hurdle crews may face during future missions, while another is the limited time astronauts have to complete tasks that require human intervention. Robotic technologies, such as the Test facility for lab-aUtomation System in Kibo (TUSK), may help address these time constraints. This investigation studies how microgravity affects delicate robotic operations that rely on precise movement. Insights could help improve the design of future automated systems that can execute tasks independently, freeing up astronauts’ valuable time during future missions.

Studying the body in space

Astronauts also serve as test subjects. They collect biological samples, conduct medical exams, and perform scans to understand how bodies adapt to life in space. This research helps scientists and medical personnel understand the effects of spaceflight and protects crew health as missions extend farther into the solar system.
 
Past research shows weightlessness during spaceflight can sometimes disrupt astronauts’ normal blood flow, which may increase health risks for conditions, such as blood clots.The Spaceflight Thrombosis and Risk Factors (Venous Haemostasis) experiment examines changes in blood flow to identify unique physiological correlations and create preventative measures for at-risk crew members.
 
Astronauts also may experience changes to their cardiovascular and respiratory systems during spaceflight, which could affect blood pressure regulation. Research with the Causal Analysis of Cardiorespiratory Coupling on the ISS (CARDIOBREATH) uses the Bio-Monitor “smart shirt” to track heart rate, blood pressure, breathing rate, and activity during exercise sessions aboard the orbiting complex. Results will improve understanding of cardiovascular health in microgravity and inform treatments for cardiorespiratory risks during and after long-duration missions.
 
Maintaining mental health in space is as important as physical health. Prolonged isolation and confinement can impact a crew member’s sleep, morale, and decision-making. The Mind/Body Practices for Deep Space Exploration (RelaxPro) experiment evaluates non-invasive practices, such as meditation, to develop a structured system to reduce stress and improve sleep on future missions.

Refining next-generation spaceflight 

Spacecraft are a critical aspect of deep space missions, providing shelter from the harsh environment of space, along with oxygen, water, and other life-support systems. Testing systems aboard the International Space Station allows researchers to refine technologies for next generation spacecraft traveling beyond low Earth orbit.

The Fiber-optic Active Dosimeter (Lumina) demonstrates real-time radiation monitoring using optical fibers that darken when exposed to radiation. Monitoring ionizing radiation keeps astronauts safe and remains one of the key challenges for future deep space exploration.

Many spacecraft use cryogenic, or extremely cold, fuels for propulsion. These fuels must remain cold to stay in liquid form, but temperature fluctuations in space can cause them to slowly evaporate and escape the tank, affecting fuel efficiency. The Zero Boil-Off Tank Noncondensables (ZBOT-NC)investigation evaluates how gases that do not liquify at low temperatures impact pressure control, evaporation, and condensation rates inside propellant tanks. Data from this experiment will help validate models and support the design of more efficient cryogenic fuel storage systems.

As the crew’s living environment, the spacecraft must also be monitored for microbial activity to help ensure a safe and healthy habitat. The Genomic Enumeration of Antibiotic Resistance in Space (GEARS) investigation surveys the space station for antibiotic-resistant organisms to better understand how bacteria may adapt in space. The study uses DNA sequencing techniques to advance onsite identification and diagnostic capabilities that will be important for future missions.

International Space Station science still is buzzing for the remainder of 2026. To learn more about ongoing research aboard the space station, visit:

NASA.gov/ISS-Research 

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4 Min Read

Lion Nebula Roars to Life With NASA’s Webb

Observing across the starry “plains” of space, NASA’s James Webb Space Telescope has taken new images of NGC 2392, nicknamed the Lion Nebula. NASA’s Hubble Space Telescope previously viewed this planetary nebula in 2000, imaging the lion face-shaped target in visible light and revealing features such as the “mane” of hazy, comet-shaped objects. Now Webb has captured a clearer, more detailed view of the Lion Nebula due to its high-resolution imaging.

Lion Nebula (NIRCam and MIRI Image)

At first glance the nebula’s overall structure in Webb’s infrared images, with both the NIRCam (Near Infrared Camera) and MIRI (Mid Infrared Instrument) instruments, may look quite similar to Hubble’s earlier visible-light view. However, Webb’s infrared vision highlights features like compact clumps of dust and a haze of ionized gas. It’s taken several thousand years for this collection of gas and dust to reach its current shape, and the nebula’s components continue to be altered.

The source of these constant changes and the reason for the Lion Nebula’s distinct appearance is located at the center: the remains of a dying star. Though it looks like the button nose of the lion, its energy and radiation are powering the intricate structures seen here.

Lion Nebula (MIRI Image)

Massive stars undergo supernova explosions at the end of their lives, but these kinds of events are few and far in between. Most of the universe’s stars have lower masses, like the one belonging to NGC 2392. When a lower-mass star can no longer sustain itself with nuclear reactions in its core, the star becomes unstable and pulsates, losing its mass by shedding its outer layers, which then turn into shells of gas and dust called a planetary nebula. (Stars at this life stage are responsible for producing much of the universe’s observable dust.) The star’s radiation drives the ejected material away, leaving behind the very hot stellar core, also known as a white dwarf.

In the Lion Nebula’s case, the death of the oxygen-rich central star has left behind a white dwarf that is “cooking” everything from the inside and producing a bubble of ionized gas as it does. The gas bubble, which forms the lion’s face, is expanding over time and destroying dust that is in its path. Understanding why the swept-up gas has a complex structure of rings and shells, a common feature in planetary nebulae, is an ongoing endeavor.

The mane of the lion is the interior of a dust shell that is being illuminated by the white dwarf at the center. The tufts of hair, which look like cometary tails of material, are compact clumps of dust that have survived the stellar core’s radiation and protect the material that lies behind them.

Webb’s imagery “freezes” this planetary nebula in time, though the star’s death, and its tumultuous effects, go on. NGC 2392 will continue to undergo changes as its gas and dust migrate away from the stellar core. Astronomers estimate the lion will eventually disperse in approximately 10,000 years — a relatively short period in astronomical terms.

The James Webb Space Telescope is the world’s premier space science observatory. Webb is solving mysteries in our solar system, looking beyond to distant worlds around other stars, and probing the mysterious structures and origins of our universe and our place in it. Webb is an international program led by NASA with its partners, ESA (European Space Agency) and CSA (Canadian Space Agency).

To learn more about Webb, visit:

https://science.nasa.gov/webb

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Lion Nebula (NIRCam and MIRI Image)

NASA’s James Webb Space Telescope imaged the planetary nebula NGC 2392, the Lion Nebula, using the observatory’s NIRCam and MIRI instruments. The central star’s remains are responsible for the nebula’s structure, including a lion face-shaped bubble of ionized gas and dust “mane.”

Lion Nebula (MIRI Image)

NASA’s James Webb Space Telescope’s mid-infrared image of planetary nebula NGC 2392, nicknamed the Lion Nebula, highlights the varying dust structures. Some dust is being destroyed by the dying central star’s radiation, while some dust filaments manage to survive.

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Within each ADSEP facility there are three to four “mini-laboratories”, called cassettes, that allow multiple studies with different needs to be performed at the same time. The latest model, ADSEP-4 can accommodate four cassettes and features imagery capabilities. Since 2017, ADSEPs have conducted and supported two dozen investigations aboard space station with new ones on the horizon.

The latest ADSEP investigations are related to growing seed crystals in space, which can be used to reformulate existing drugs or develop entirely new therapeutics. Previous experiments have shown that the unique microgravity environment allows the growth of larger and higher quality crystals. With Redwire’s Pharmaceutical In-Space Laboratory (PIL-BOX), a cassette-based system that uses the ADSEP facility, researchers can grow improved, space-grown seed crystals.

Notable PIL-BOX experiments sponsored by the ISS National Laboratory have focused on cancer research. The ADSEP-PIL-10 investigation, currently being conducted in orbit in collaboration with the Aspera Biomedicines, works to crystallize cancer-blocking and cancer-promoting molecules with the goal of creating an oral cancer medication. ADSEP-PIL-15 crystalized cancer-treating medicines to help refine production, quality, and stability of these cancer drugs. A recent technology demonstration, ADSEP- ICC (Industrial Crystallization Cassette), tested a larger cassette to expand ADSEP function and scale crystallization production for commercial use.

ADSEPs are not limited to crystal growth and can also be used for culturing cells and tissues, studying organisms, and researching materials-sciences. In 2021, ADSEP-UMAMI studied how bobtail squid interacted with beneficial microbes in the space environment. This research found that symbiotic interactions with microbes can lessen a host animal’s stress responses caused by spaceflight and accelerate developmental pathways such as growing neurons and tissues. These findings give insight into the importance of symbiotic relationships in closed ecosystems like spacecraft and have implications for astronauts and their own beneficial bacteria during space missions.

The automation and versatility of ADSEPs permit a wide array of science experiments to be conducted aboard the orbiting laboratory, leading to findings that inform future space missions and are beneficial to people on Earth.